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1994-10-25
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Document 2960
DOCN M94A2960
TI Upper digestive tract endoscopy in HIV infected patient.
DT 9412
AU Aoki FH; Meirelles JO; Monteiro DT; Lima J; Abreu W; Pavan M; Inf. Dis.
Division-FMSc-St. Univ. of Campinas-Cps-SP-Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):185 (abstract no. PB0169). Unique
Identifier : AIDSLINE ICA10/94369615
AB OBJECTIVES: To evaluate the main injuries observed in upper digestive
tract endoscopy in patients infected with HIV, histopathologic changes
and infectious agents found in the biopsy samples. METHODS: A
retrospective analysis on one hundred endoscopies from 83 patients who
were infected with HIV and followed in the Infectious Diseases Division
at the State University of Campinas during the year 1993. The mean age
of the studied population was 34 (18-68) years being that 68 (81,9%)
were men and 15 (18,1%) were women. The risk factors for HIV infection
were: IVDU-29 (34,9%); promiscuous heterosexual -13 (15,6%); homosexual
- 10 (12,0%); sexual contact with HIV+ - 10 (12,0%); bisexual - 06
(7,2%); IVDU/bisexual - 04 (4,8%); IVDU/homosexual - 01 (1,2%);
hemophiliac - 01 (1,2%). Nine cases had no information about risk
factors. RESULTS: Eighty (96,38%) patients reported previous or
concomitant disease at the time of endoscopy: moniliasis - 54 (67,5%);
tuberculosis - 29 (36,2%); Pneumocystis carinii pneumonia - 21 (26,2%);
herpetic infection - 21 (26,2%); toxoplasmosis - 16 (20,0%); hairy
leucoplasia - 13 (15,6%); cytomegalovirus - 11 (13,7%); cryptococcosis -
08 (10%); syphilis - 06 (7,5%); isosporiasis - 05 (6,2%); Kaposi's
sarcoma 05 (6,2%). Sixty one (73,4%) patients reported gastrointestinal
symptoms; epigastric pain - 29 (47,5%); diarrhea - 23 (37,1%); pyrosis -
18 (29,5%); vomit - 16 (26,2%); substernal pain - 14 (23%); nausea and
dysphagia - 13 (21,3%). Gastrointestinal tract symptoms, fever, loss of
weight and Kaposi's sarcoma staging determined the performance of the
upper digestive tract endoscopy. Moniliasis - 39 (39%); cellular changes
of HPV - 25 (25%), cytomegalovirus - 09 (9%); H. pylori - 08 (8%);
cryptosporidiosis - 04 (4%); mycobacteria - 04 (4%); Kaposi's sarcoma -
03 (3%) and HSV - 01 (1%) were the diagnosis more frequently found.
DISCUSSION: Endoscopic findings for moniliasis, HPV and CMV were
confirmed by histopathologic tests. Only four cases of Mycobacteria
infection were detected by means of culture test (few number of samples
for performing this test). It is important realize endoscopies in these
cases: discover new diagnostics and to confirm them.
DE Acquired Immunodeficiency Syndrome/*PATHOLOGY Adolescence Adult Aged
AIDS-Related Opportunistic Infections/*PATHOLOGY Biopsy Endoscopy,
Gastrointestinal/*INSTRUMENTATION Female Gastrointestinal
Diseases/*PATHOLOGY Gastrointestinal System/PATHOLOGY Human Male
Middle Age MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).